Genome databases

Journal Article · Fri Oct 11 00:00:00 EDT 1991 · Science (Washington, D.C.); (United States)

DOI:https://doi.org/10.1126/science.1925577· OSTI ID:5602639

Courteau, J

Since the Genome Project began several years ago, a plethora of databases have been developed or are in the works. They range from the massive Genome Data Base at Johns Hopkins University, the central repository of all gene mapping information, to small databases focusing on single chromosomes or organisms. Some are publicly available, others are essentially private electronic lab notebooks. Still others limit access to a consortium of researchers working on, say, a single human chromosome. An increasing number incorporate sophisticated search and analytical software, while others operate as little more than data lists. In consultation with numerous experts in the field, a list has been compiled of some key genome-related databases. The list was not limited to map and sequence databases but also included the tools investigators use to interpret and elucidate genetic data, such as protein sequence and protein structure databases. Because a major goal of the Genome Project is to map and sequence the genomes of several experimental animals, including E. coli, yeast, fruit fly, nematode, and mouse, the available databases for those organisms are listed as well. The author also includes several databases that are still under development - including some ambitious efforts that go beyond data compilation to create what are being called electronic research communities, enabling many users, rather than just one or a few curators, to add or edit the data and tag it as raw or confirmed.

• OSTI ID: 5602639
• Journal Information: Science (Washington, D.C.); (United States), Vol. 254:5029; ISSN 0036-8075
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
GENETIC MAPPING
RESEARCH PROGRAMS
CHROMOSOMES
DATA PROCESSING
DNA SEQUENCING
DROSOPHILA
ESCHERICHIA COLI
MAN
MICE
NEMATODES
PROTEIN STRUCTURE
YEASTS
ANIMALS
ARTHROPODS
ASCHELMINTHES
BACTERIA
DIPTERA
EUMYCOTA
FLIES
FRUIT FLIES
FUNGI
HELMINTHS
INSECTS
INVERTEBRATES
MAMMALS
MAPPING
MICROORGANISMS
PLANTS
PRIMATES
PROCESSING
RODENTS
STRUCTURAL CHEMICAL ANALYSIS
VERTEBRATES
550400* - Genetics