Effect of thallium-201 blood levels on reversible myocardial defects

Journal Article · Sat Jul 01 04:00:00 EDT 1989 · J. Nucl. Med.; (United States)

OSTI ID:5601758

Nelson, C W; Wilson, R A; Angello, D A; Palac, R T

To determine if /sup 201/Tl plasma blood levels correlate with the presence of reversible myocardial defects during exercise testing, 14 patients with stable coronary artery disease underwent two separate exercise /sup 201/Tl stress tests. Between initial and delayed imaging, on one test the patients drank an instant breakfast drink (eating) and on the other they drank an equivalent volume of water as a control (H/sub 2/O). Thallium-201 imaging was performed immediately postexercise, immediately after eating/H/sub 2/O and 210 min after eating/H/sub 2/O. Between initial and immediate post eating/H/sub 2/O images 201Tl reversible defects occurred in 27/38 regions in the H/sub 2/O test versus 15/38 regions in the eating test (p = 0.02). Over this early time period, plasma /sup 201/Tl activity was significantly higher in the H/sub 2/O test than eating test (p less than 0.05). In conclusion, early reversal of /sup 201/Tl defects may, in part, be the result of higher plasma /sup 201/Tl activity early after initial postexercise /sup 201/Tl imaging.

• Research Organization: Oregon Health Sciences Univ., Portland (USA)
• OSTI ID: 5601758
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 30:7; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ALDEHYDES
ANIMALS
BETA DECAY RADIOISOTOPES
BODY
CARBOHYDRATES
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
EXERCISE
FASTING
GLUCOSE
HEART
HEAVY NUCLEI
HEXOSES
HORMONES
INSULIN
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MAN
MONOSACCHARIDES
MUSCLES
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
PEPTIDE HORMONES
PRIMATES
RADIOISOTOPE SCANNING
RADIOISOTOPES
SACCHARIDES
SECONDS LIVING RADIOISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
UPTAKE
VERTEBRATES