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Perfusion of nonventilated lung: failure of hypoxic vasoconstriction

Journal Article · · AJR, Am. J. Roentgenol.; (United States)
Alveolar hypoxia is a well established cause of regional vasoconstriction such that nonventilated segments are not perfused. The paradoxical situation of retained perfusion of nonventilated lung has seldom been discussed. Three clinical examples are illustrated. In each case coexistent chronic obstructive lung disease may have contributed to this unexpected finding by reducing pulmonary vascular capacity such that blood flow diversion from hypoxic segments was not possible.
Research Organization:
Yale-New Haven Hospital, CT
OSTI ID:
5589357
Journal Information:
AJR, Am. J. Roentgenol.; (United States), Journal Name: AJR, Am. J. Roentgenol.; (United States) Journal Issue: 1 Vol. 141:1; ISSN AAJRD
Country of Publication:
United States
Language:
English