Simultaneous determination of trace elements in lavage fluids from human bronchial alveoli by energy-dispersive x-ray fluorescence. 3. Routine analysis
Journal Article
·
· Clin. Chem. (Winston-Salem, N.C.); (United States)
OSTI ID:5589275
We applied the energy-dispersive x-ray fluorescence technique to determination of trace elements in human bronchoalveolar lavage fluids. Our analysis of more than 200 samples allowed us to determine normal reference values, to be used in characterizing occupational exposure. These values are expressed both in nanograms per 1000 cells (of all kinds) and nanograms per 1000 macrophages to correlate lavage efficiency and dust content of the alveoli. The result expressed in milligrams per liter is not sufficient, because some healthy volunteers showed high concentrations of iron but normal values when expressed vs the number of cells. Some examples of abnormal compositions of broncho-alveolar lavages are reported and the fully automated spectrometer developed for clinical and biological investigations is described.
- Research Organization:
- Ecole Europeenne des Hautes Etudes des Industries Chimiques Laboratoire de Chimie Minerale, Strasbourg, France
- OSTI ID:
- 5589275
- Journal Information:
- Clin. Chem. (Winston-Salem, N.C.); (United States), Journal Name: Clin. Chem. (Winston-Salem, N.C.); (United States) Vol. 33:12; ISSN CLCHA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Simultaneous determination of trace elements in lavage fluids from human bronchial alveoli by energy-dispersive x-ray fluorescence. 2: Determination of abnormal lavage contents and verification of the results
Simultaneous determination of trace elements in lavage fluids from human bronchial alveoli by energy dispersive x-ray fluorescence. 1: Technique and determination of the normal reference interval
Enhanced reactive oxygen species metabolism of air space cells in hypersensitivity pneumonitis
Journal Article
·
Mon Mar 31 23:00:00 EST 1986
· Clin. Chem. (Winston-Salem, N.C.); (United States)
·
OSTI ID:5526761
Simultaneous determination of trace elements in lavage fluids from human bronchial alveoli by energy dispersive x-ray fluorescence. 1: Technique and determination of the normal reference interval
Journal Article
·
Sun Mar 31 23:00:00 EST 1985
· Clin. Chem. (Winston-Salem, N.C.); (United States)
·
OSTI ID:5411063
Enhanced reactive oxygen species metabolism of air space cells in hypersensitivity pneumonitis
Journal Article
·
Sat Jun 01 00:00:00 EDT 1991
· Journal of Laboratory and Clinical Medicine; (United States)
·
OSTI ID:5395209
Related Subjects
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL MATERIALS
BODY FLUIDS
BRONCHI
CALIBRATION STANDARDS
CHEMICAL ANALYSIS
CHEMICAL COMPOSITION
COPPER
ELEMENTS
IRON
LAVAGE
MAMMALS
MAN
MANGANESE
MATERIALS
METABOLISM
METALS
NONDESTRUCTIVE ANALYSIS
OCCUPATIONAL EXPOSURE
PRIMATES
RESPIRATORY SYSTEM
STANDARDS
TRACE AMOUNTS
TRANSITION ELEMENTS
UPTAKE
VERTEBRATES
X-RAY EMISSION ANALYSIS
X-RAY FLUORESCENCE ANALYSIS
ZINC
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL MATERIALS
BODY FLUIDS
BRONCHI
CALIBRATION STANDARDS
CHEMICAL ANALYSIS
CHEMICAL COMPOSITION
COPPER
ELEMENTS
IRON
LAVAGE
MAMMALS
MAN
MANGANESE
MATERIALS
METABOLISM
METALS
NONDESTRUCTIVE ANALYSIS
OCCUPATIONAL EXPOSURE
PRIMATES
RESPIRATORY SYSTEM
STANDARDS
TRACE AMOUNTS
TRANSITION ELEMENTS
UPTAKE
VERTEBRATES
X-RAY EMISSION ANALYSIS
X-RAY FLUORESCENCE ANALYSIS
ZINC