Summary of carcinogenic potency and positivity for 492 rodent carcinogens in the Carcinogenic Potency Database
Journal Article
·
· Environmental Health Perspectives; (USA)
- Lawrence Berkeley Lab., CA (USA)
A tabulation of carcinogenic potency (TD{sub 50}) by species for 492 chemicals that induce tumors in rats or mice is presented. With the use of the Carcinogenic Potency Database, experimental results are summarized by indicating in which sex-species groups the chemical was tested and the respective evaluations of carcinogenicity. A comparison of three summary measures of TD{sub 50} for chemicals with more than one positive experiment per species shows that the most potent TD{sub 50} value is similar to measures that average values or functions of values. This tabulation can be used to investigate associations between rodent potency and other factors such as mutagenicity, teratogenicity, chemical structure, and human exposure.
- OSTI ID:
- 5584630
- Journal Information:
- Environmental Health Perspectives; (USA), Journal Name: Environmental Health Perspectives; (USA) Vol. 79; ISSN 0091-6765; ISSN EVHPA
- Country of Publication:
- United States
- Language:
- English
Similar Records
An overview of the report: Correlation between carcinogenic potency and the maximum tolerated dose: Implications for risk assessment
Development of quantitative structure-activity relationship (QSAR) models to predict the carcinogenic potency of chemicals
Predicting the carcinogenicity of chemicals in humans from rodent bioassay data
Journal Article
·
Sun Aug 01 00:00:00 EDT 1993
· Risk Analysis; (United States)
·
OSTI ID:5594211
Development of quantitative structure-activity relationship (QSAR) models to predict the carcinogenic potency of chemicals
Journal Article
·
Wed Jan 14 23:00:00 EST 2009
· Toxicology and Applied Pharmacology
·
OSTI ID:21182707
Predicting the carcinogenicity of chemicals in humans from rodent bioassay data
Journal Article
·
Thu Aug 01 00:00:00 EDT 1991
· Environmental Health Perspectives; (United States)
·
OSTI ID:6097652