Prenatal x-ray and childhood cancer in twins
Thesis/Dissertation
·
OSTI ID:5584626
In order to evaluate the causal nature of the relationship between prenatal x-ray exposure and childhood cancer, a case control study was conducted in a population of over 32,000 twins born in the state of Connecticut from 1930-1969 and followed to age 15. Thirty-two incident cancer cases were identified by linking the Connecticut Twin and Tumor registries. Each case was matched with four controls on year of birth, sex, race, and survival. Prenatal x-ray information as well as reproductive, delivery and birth data were obtained from the hospital of birth, the physician providing prenatal care, private radiology groups and interviews with hospital staff. The case control study which obtained exposure information on selected subjects found an increased risk of childhood cancer from prenatal x-ray exposure. The risk associated with radiation exposure was elevated in the following subcategories: mother with history of pregnancy loss, a gravity greater than 1, under 30 years of age, and twins weighing five pounds or more at birth. The results, though based on small numbers, strengthen the association between prenatal x-ray exposure and childhood cancer.
- Research Organization:
- Johns Hopkins Univ., Baltimore, MD (USA)
- OSTI ID:
- 5584626
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE GROUPS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOMEDICAL RADIOGRAPHY
CHILDREN
DELAYED RADIATION EFFECTS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTROMAGNETIC RADIATION
EPIDEMIOLOGY
HEMIC DISEASES
IONIZING RADIATIONS
IRRADIATION
LEUKEMIA
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
PRENATAL EXPOSURE
PRENATAL IRRADIATION
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOLOGY
X RADIATION
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE GROUPS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOMEDICAL RADIOGRAPHY
CHILDREN
DELAYED RADIATION EFFECTS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTROMAGNETIC RADIATION
EPIDEMIOLOGY
HEMIC DISEASES
IONIZING RADIATIONS
IRRADIATION
LEUKEMIA
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
PRENATAL EXPOSURE
PRENATAL IRRADIATION
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOLOGY
X RADIATION