Diagnosis and management of endocrine gland neoplasms

Conference · Mon May 01 04:00:00 EDT 1989

OSTI ID:5576143

Weller, R E

Functional and nonfunctional neoplasms of the endocrine glands constitute some of the more challenging diagnostic and therapeutic problems in veterinary cancer medicine. The clinical signs are usually the result of an overproduction of hormones that are normally biosynthesized by the neoplastic endocrine gland (orthoendocrine syndromes), as opposed to those that are the result of hormones that are not normally biosynthesized and secreted by those cells that have undergone neoplastic transformation (paraendocrine syndromes, also known as endocrine paraneoplastic syndromes or ectopic hormone syndromes). The biological effects produced by a neoplasm may be out of proportion to the actual size of the tumor. This report focuses on the clinical signs and syndromes associated with neoplasms of the thyroid, adrenal glands and pancreas. Discussion will focus on the mechanisms producing the clinical signs, diagnosis, staging, therapy and prognosis. 2 tabs.

• Research Organization: Pacific Northwest Lab., Richland, WA (USA)
• Sponsoring Organization: DOE; USDOE, Washington, DC (USA)
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 5576143
• Report Number(s): PNL-SA-17044; CONF-8905379--1; ON: DE91012920
• Country of Publication: United States
• Language: English

Related Subjects

550200 -- Biochemistry
550600* -- Medicine
551000 -- Physiological Systems
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
ADRENAL GLANDS
ADRENAL HORMONES
ANIMAL CELLS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOSYNTHESIS
BODY
CARCINOMAS
CELL TRANSFORMATIONS
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
DOGS
ENDOCRINE GLANDS
GLANDS
HORMONES
INSULIN
INTERMEDIATE MASS NUCLEI
IODINE 131
IODINE ISOTOPES
ISOTOPES
MAMMALS
MEDICINE
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ONCOGENIC TRANSFORMATIONS
ORGANS
PANCREAS
PARATHORMONE
PEPTIDE HORMONES
PRODUCTION
RADIOISOTOPES
SYNTHESIS
THERAPY
THYROID
THYROID HORMONES
VERTEBRATES
VETERINARY MEDICINE