Interface of a microbore high-performance liquid chromatography with a diffuse reflectance Fourier transform infrared spectrometer

Journal Article · Mon Apr 01 04:00:00 EST 1985 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac00281a011· OSTI ID:5576050

Conroy, C M; Griffiths, P R; Jinno, K

Some of the problems commonly encountered in high-performance liquid chromatography (HPLC)/Fourier transform infrared spectrometry (FT-IR) can be alleviated through the use of microbore HPLC (..mu..HPLC) columns. An interface based on a solvent elimination technique and utilizing the microsampling capability of diffuse reflectance (DR) FT-IR has been designed for use with ..mu..HPLC. Detection limits achieved with the interface are about an order of magnitude lower than those previously reported. Several different microbore columns were studied and the relative advantages and disadvantages of each, with respect to the interface, are discussed. 28 references, 5 figures.

• Research Organization: Univ. of California, Riverside
• OSTI ID: 5576050
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 57:4; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
400104 -- Spectral Procedures-- (-1987)
ALCOHOLS
ALKANES
CHROMATOGRAPHY
DATA
DISPERSIONS
EQUIPMENT INTERFACES
EXPERIMENTAL DATA
FLOW RATE
FOURIER TRANSFORM SPECTROMETERS
HEXANE
HYDROCARBONS
HYDROXY COMPOUNDS
INFORMATION
INFRARED SPECTRA
INFRARED SPECTROMETERS
LIQUID COLUMN CHROMATOGRAPHY
MEASURING INSTRUMENTS
METHANOL
MIXTURES
NUMERICAL DATA
ORGANIC COMPOUNDS
PERFORMANCE
PHASE STUDIES
SAMPLE PREPARATION
SEPARATION PROCESSES
SOLUBILITY
SOLUTIONS
SOLVENT PROPERTIES
SPECTRA
SPECTROMETERS