Improved determination of cadmium in blood and plasma by flameless atomic absorption spectroscopy

Journal Article · Mon Mar 31 23:00:00 EST 1986 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01623541· OSTI ID:5573835

Roberts, C A; Clark, J M

Recently reported analytical methods for determining cadmium in biological fluids indicate accurate and reproducible results but are quite limited by a low working range. Many flameless atomic absorption methods for assaying nanogram quantities of cadmium have relied upon extraction procedures prior to analysis. These techniques can be susceptible to errors by sample contamination or loss while carrying out the many steps of sample preparation. In the method described here, nanogram quantities of cadmium in blood and plasma are measured by using graphite furnace atomic absorption spectroscopy facilitated by a wet ashing pretreatment of samples. The method appears to be quite accurate and reproducible with an average coefficient of variation of 6.7%. The linear working range of the method was found to extend from 0.4 ..mu..g Cd/l to 16.0 ..mu..g Cd/l.

• Research Organization: Navy, Long Beach, CA
• OSTI ID: 5573835
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 36:4; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION SPECTROSCOPY
ACCURACY
ANIMALS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CHEMISTRY
BLOOD PLASMA
BLOOD SERUM
BODY FLUIDS
CADMIUM CHLORIDES
CADMIUM COMPOUNDS
CADMIUM HALIDES
CHLORIDES
CHLORINE COMPOUNDS
HALIDES
HALOGEN COMPOUNDS
MAMMALS
MATERIALS
RABBITS
SAMPLE PREPARATION
SPECTROSCOPY
VERTEBRATES