Information profiles on potential occupational hazards: Nitroparaffins. Draft report (Second)

Technical Report · Sun Nov 01 04:00:00 EST 1981

OSTI ID:5559105

Profiles of information are presented for the following nitroparaffins: nitroethane, nitromethane, l-nitropropane, 2-nitropropane, tetranitromethane, and trinitromethane. Oral and inhalation toxicities and the degree of histological damage increase with increasing molecular weight of the compounds. The primary effects include histological liver damage and central nervous system depression, both atactic and narcotic changes, regardless of the route of administration or the duration of exposure. Vapor exposures also cause respiratory tract and conjunctival irritation and pulmonary edema. Symptoms of exposure in humans include headache, nausea, damage to the respiratory tract, and liver damage. Most of the exposures to nitroparaffins resulting from occupational pursuits have been to 2-nitropropane.

• Research Organization: Syracuse Research Corp., NY (USA). Center for Chemical Hazard Assessment
• OSTI ID: 5559105
• Report Number(s): PB-89-215784/XAB; SRC-TR--81-617
• Country of Publication: United States
• Language: English

Related Subjects

552000 -- Public Health
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS
ALKANES
BIOLOGICAL EFFECTS
CHEMICAL ANALYSIS
CONTROL EQUIPMENT
EQUIPMENT
HYDROCARBONS
INDUSTRIAL MEDICINE
MATERIALS
MEDICINE
NITRO COMPOUNDS
OCCUPATIONAL EXPOSURE
OCCUPATIONAL SAFETY
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
OTHER ORGANIC COMPOUNDS
PARAFFIN
PRODUCTION
SAFETY
TOXIC MATERIALS
TOXICITY
WAXES