Effects of feeding lactobacillus GG on lethal irradiation in mice

Journal Article · Fri May 01 00:00:00 EDT 1987 · Diagn. Microbiol. Infect. Dis.; (United States)

DOI:https://doi.org/10.1016/0732-8893(87)90063-0· OSTI ID:5553593

Dong, M Y; Chang, T W; Gorbach, S L

Mice exposed to 1400 rads of total body irradiation experienced 80%-100% mortality in 2 wk. Bacteremia was demonstrated in all dead animals. Feeding Lactobacillus GG strain reduced Pseudomonas bacteremia and prolonged survival time in animals colonized with this organism. In animals not colonized with Pseudomonas, feeding Lactobacillus GG also produced some reduction in early deaths, and there was less Gram-negative bacteremia in these animals compared with controls.

• Research Organization: Tufts Univ. School of Medicine Boston, MA
• OSTI ID: 5553593
• Journal Information: Diagn. Microbiol. Infect. Dis.; (United States), Vol. 7:1
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
LACTOBACILLUS
RADIOSENSITIVITY EFFECTS
PSEUDOMONAS
INFECTIVITY
INTESTINES
LETHAL IRRADIATION
MICE
RADIATION PROTECTION
SEPTICEMIA
SURVIVAL TIME
WHOLE-BODY IRRADIATION
ANIMALS
BACTERIA
BODY
DIGESTIVE SYSTEM
EXTERNAL IRRADIATION
GASTROINTESTINAL TRACT
IRRADIATION
MAMMALS
MICROORGANISMS
ORGANS
RODENTS
VERTEBRATES
560152* - Radiation Effects on Animals- Animals