Effects of feeding lactobacillus GG on lethal irradiation in mice

Journal Article · Fri May 01 00:00:00 EDT 1987 · Diagn. Microbiol. Infect. Dis.; (United States)

DOI:https://doi.org/10.1016/0732-8893(87)90063-0· OSTI ID:5553593

Dong, M Y; Chang, T W; Gorbach, S L

Mice exposed to 1400 rads of total body irradiation experienced 80%-100% mortality in 2 wk. Bacteremia was demonstrated in all dead animals. Feeding Lactobacillus GG strain reduced Pseudomonas bacteremia and prolonged survival time in animals colonized with this organism. In animals not colonized with Pseudomonas, feeding Lactobacillus GG also produced some reduction in early deaths, and there was less Gram-negative bacteremia in these animals compared with controls.

• Research Organization: Tufts Univ. School of Medicine Boston, MA
• OSTI ID: 5553593
• Journal Information: Diagn. Microbiol. Infect. Dis.; (United States), Journal Name: Diagn. Microbiol. Infect. Dis.; (United States) Vol. 7:1; ISSN DMIDD
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BACTERIA
BODY
DIGESTIVE SYSTEM
EXTERNAL IRRADIATION
GASTROINTESTINAL TRACT
INFECTIVITY
INTESTINES
IRRADIATION
LACTOBACILLUS
LETHAL IRRADIATION
MAMMALS
MICE
MICROORGANISMS
ORGANS
PSEUDOMONAS
RADIATION PROTECTION
RADIOSENSITIVITY EFFECTS
RODENTS
SEPTICEMIA
SURVIVAL TIME
VERTEBRATES
WHOLE-BODY IRRADIATION