Different indices of exposure and respiratory function outcomes in the epidemiologic assessment of high air pollution exposure in children

Conference · · Archives of Environmental Health; (USA)

OSTI ID:5548379

Castillejos, M ^[1]; Santos-Burgoa, C ^[2]

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1. Colegio de Mexico (Mexico)
2. National Institute of Public Health (Mexico)

The physiologic effects of ozone exposure have been documented through laboratory research and some epidemiologic studies. Some metropolitan areas in Mexico City have repeatedly had very high levels of ozone exposures for long periods. A non-representative sample of school-age children living in such areas was selected and followed up for 6 mo; the differences in their pulmonary function tests were assessed. A series of methodologic issues came to light while exploring the data, referring to the different indices of exposure and outcome. In many epidemiologic studies, MMF is considered to have very high variability, but this population seemed to perform acceptably in relation to FEV and FVC. Also, several exposure indices were constructed trying to model the effective cumulative exposure. The longitudinal models constructed were discussed for ozone; other pollutants will be added later.

• OSTI ID: 5548379
• Report Number(s): CONF-890937-; CODEN: AEHLA
• Journal Information: Archives of Environmental Health; (USA), Vol. 45:5; Conference: 1. annual meeting of the International Society for Environmental Epidemiology, Upton, NY (USA), 13-15 Sep 1989; ISSN 0003-9896
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
59 BASIC BIOLOGICAL SCIENCES
OZONE
HEALTH HAZARDS
AIR POLLUTION
CHILDREN
CHRONIC EXPOSURE
MAN
MEXICO
RESPIRATORY SYSTEM DISEASES
URBAN AREAS
AGE GROUPS
ANIMALS
DEVELOPING COUNTRIES
DISEASES
HAZARDS
LATIN AMERICA
MAMMALS
NORTH AMERICA
POLLUTION
PRIMATES
VERTEBRATES
540110*
550900 - Pathology