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U.S. Department of Energy
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Effects of compounds produced from petroleum utilization on marine invertebrates with emphasis on neoplasia and carcinogenesis

Book ·
OSTI ID:5546342
The objectives of this program are: (1) to determine the concentration (body burdens) of selected environmental chemical carcinogens in economically-important mollusks and crustaceans from Oregon bays, estuaries and inshore areas; (2) to determine if there is a potential public health hazard to man from consuming shellfish, harvested from Oregon bays, estuaries and inshore areas, which contain petroleum by-products that are carcinogenic; (3) to survey populations of bivalue mollusks, determine the incidence of neoplastic diseases in these populations and ascertain if there is any correlation between carcinogenic body burdens and the incidences of such diseases; (4) to identify point sources of chemical carcinogens that are present in Oregon bays and estuaries utilized in this study; and (5) to determine rates of carcinogenic polycyclic aromatic hydrocarbon uptake and elimination in bivalue mollusks. Extensive preliminary investigations have been conducted to: determine which Oregon bays will be utilized in the study; ascertain which shellfish species will be used; locate sites at which shellfish can be continuously sampled. Bivalue mollusks from different habitats in the various bays are analyzed for the presence and amount of benzo(a)pyrene (BAP) monthly or bi-monthly. Histological sections are prepared so that diagnoses can be made and neoplastic diseases, if present, can be identified.
OSTI ID:
5546342
Country of Publication:
United States
Language:
English