Membrane-membrane interactions in a lipid-containing bacteriophage system. Progress report, October 1, 1978-September 30, 1979. [Hydrophobic membrane perturbers as antiviral agents]

Technical Report · Fri Jun 01 00:00:00 EDT 1979

DOI:https://doi.org/10.2172/5545258· OSTI ID:5545258

Snipes, W.

Progress is reported on research on two aspects of the life cycle of PM2, a lipid-containing bacteriophage. The first concerns the initial interaction of PM2 with the outer membrane of its host cell, Pseudomonas BAL-31. The second concerns the assembly of PM2 in infected cells and the structural features of hydrophobic membrane perturbers that inhibit PM2 assembly. Several other projects have been completed: distribution of PM2 receptors; effects of adamantance derivatives on PM2 production; hydrophobic membrane perturbers as antiviral and virucidal agents; hydrophobic photosensitizers; and other technique development. (ACR)

• Research Organization: Pennsylvania State Univ., University Park (USA). Coll. of Science
• OSTI ID: 5545258
• Report Number(s): COO-2311-30
• Country of Publication: United States
• Language: English

Related Subjects

550700* -- Microbiology
560130 -- Radiation Effects on Microorganisms
560301 -- Chemicals Metabolism & Toxicology-- Cells-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BACTERIA
BACTERIOPHAGES
BIOCHEMICAL REACTION KINETICS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CELL CONSTITUENTS
CELL MEMBRANES
KINETICS
LIPIDS
MEMBRANES
MICROORGANISMS
ORGANIC COMPOUNDS
PARASITES
PHOTOSENSITIVITY
PLAQUE FORMATION
PSEUDOMONAS
RADIATION EFFECTS
REACTION KINETICS
SENSITIVITY
VIRUSES