Blood volume and plasma protein responses to heat acclimatization in humans

Journal Article · Sun Mar 01 04:00:00 EST 1981 · J. Appl. Physiol.: Respir., Environ. Exercise Physiol.; (United States)

OSTI ID:5529432

Harrison, M H; Edwards, R J; Graveney, M J; Cochrane, L A; Davies, J A

The effects of heat acclimatization on intravascular volume and protein responses to acute heat stress and exercise were studied in six male subjects. Absolute values for hematocrit and hemoglobin concentration were lower after acclimatization, indicating hemodilution. Also, after acclimatization, the magnitude of the hemoconcentration response to exercise in the heat was significantly increased. There was no change in the concentration of plasma protein during or after acclimatization compared with before acclimatization, but there was a net increase in the total intravascular protein content. It is suggested that the hemodilution associated with heat acclimatization may be explained in terms of an increase in the intravascular oncotic pressure following an exercise-induced augmentation of protein, occurring at the expense of the interstitial compartment. It is concluded that this hemodilution is unlikely to be primarily responsible for the cardiovascular adjustment accompanying heat acclimatization and that it should be regarded as a secondary feature of adaptation to heat.

• Research Organization: RAF, Institute of Aviation Medicine, Farnborough, Hants., England
• OSTI ID: 5529432
• Journal Information: J. Appl. Physiol.: Respir., Environ. Exercise Physiol.; (United States), Journal Name: J. Appl. Physiol.: Respir., Environ. Exercise Physiol.; (United States) Vol. 50; ISSN JARPD
• Country of Publication: United States
• Language: English

Related Subjects

551000* -- Physiological Systems
59 BASIC BIOLOGICAL SCIENCES
ANIMALS
BIOLOGICAL ADAPTATION
BIOLOGICAL MATERIALS
BLOOD
BLOOD PLASMA
BLOOD VESSELS
BODY
BODY FLUIDS
BODY TEMPERATURE
CARBOXYLIC ACIDS
CARDIOVASCULAR SYSTEM
ENERGY
EXERCISE
GLOBIN
HEAT
HEMOGLOBIN
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
MAMMALS
MAN
MATERIALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PIGMENTS
PORPHYRINS
PRIMATES
PROTEINS
TEMPERATURE EFFECTS
TOLERANCE
VERTEBRATES
VOLUME
WEIGHT