Radioprotection by Acclimatization to Cold
The effect of acclimatization to cold on the effects of acute and chronic whole-body exposure to Co60 gamma rays was studied in rats. Acclimatization to 6 un. Concent 85% C was accompanied by a marked increase in radiation resistance. A radiation protection factor of about 2 was obtained at the LD0 level. The protective action of cold acclimatization was found to last for at least one week after the rats were returned to a normal environment. The LD0 for cold acclimatized chronic irradiated rats was significantly higher than the LD100 for the same animals submitted to an acute dose of gamma rays. Finally, it is suggested that cold acclimatization makes it possible to obtain rats that have survived a large dose of radiation for use in studies of late pathological and genetic effects of irradiation.
- Research Organization:
- Universite Laval, Quebec
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-17-023226
- OSTI ID:
- 4712439
- Journal Information:
- Nature (London), Journal Name: Nature (London) Journal Issue: 4880 Vol. 198; ISSN 0028-0836
- Publisher:
- Nature Publishing Group
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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