Mutagenicity and cytotoxicity of coal fly ash from fluidized-bed and conventional combustion

Journal Article · Fri Oct 01 04:00:00 EDT 1982 · J. Toxicol. Environ. Health; (United States)

DOI:https://doi.org/10.1080/15287398209530277· OSTI ID:5523004

Mumford, J L; Lewtas, J

Two respirable coal fly-ash samples (<3MUm) were evaluated for physical properties, chemical composition and biological activity, including cytotoxicity and mutagenicity. The two fly-ash samples were collected from a pressurized fluidized-bed combustion miniplant and from a conventional-combustion plant, both burning eastern US coal. The two samples were found to have different physical and chemical properties. Both samples were toxic in two mammalian cell systems, with fluidized bed combustion fly ash showing higher toxicity in both assay systems. For conventional-combustion fly ash, no mutagenicity was detected in bioassay of the whole particles. A series of organic solvents was employed to identify the most efficient solvent for removing mutagens from coal fly ash. Extracts of fluidized-bed combustion fly ash were found to be mutagenic when dichloromethane, acetone or cyclohexane were employed: much lower mutagenic activity was found in dichloromethane and acetone extracts of conventional combustion fly ash.

• OSTI ID: 5523004
• Journal Information: J. Toxicol. Environ. Health; (United States), Journal Name: J. Toxicol. Environ. Health; (United States) Vol. 10:4/5; ISSN JTEHD
• Country of Publication: United States
• Language: English

Related Subjects

01 COAL, LIGNITE, AND PEAT
010600 -- Coal
Lignite
&amp; Peat-- Properties &amp; Composition
016000* -- Coal
Lignite
&amp; Peat-- Health &amp; Safety
AEROSOL WASTES
ASHES
BIOASSAY
BIOLOGICAL EFFECTS
CARBONACEOUS MATERIALS
CHEMICAL COMPOSITION
CHEMICAL PROPERTIES
CHEMICAL REACTIONS
COAL
COMBUSTION
COMPARATIVE EVALUATIONS
DUSTS
ENERGY SOURCES
FLUIDIZED-BED COMBUSTION
FLY ASH
FOSSIL FUELS
FUELS
HAZARDS
HEALTH HAZARDS
MATERIALS
MUTAGEN SCREENING
MUTAGENESIS
ORGANIC SOLVENTS
OXIDATION
PHYSICAL PROPERTIES
RESIDUES
SCREENING
SOLVENTS
THERMOCHEMICAL PROCESSES
TOXICITY
WASTES