Sample collection and preparation methods affecting mutagenicity and cytotoxicity of coal fly ash
Reports by several investigators describing the biological activity of coal fly ash have presented a variety of results which in some cases are conflicting. The biological activity of coal fly ash may differ because of one or more of the following factors: (1) the samples studied were from different sources; (2) the samples were prepared for bioassay differently; (3) the sampling method differed, and, therefore, collected samples were different in chemical or physical properties which affect the biological activity. Several variables involved in coal fly ash studies -- source, sample collection land preparation methods, bioassay method -- are undoubtedly responsible for the diversity of biological effects observed. The objectives of this study were to examine the sample preparation and collection factors which may affect the observed biological activity caused by coal fly ash and to evaluate the mutagenicity and cytotoxicity of fluidized-bed combustion (FBC) fly ash from experimental and commercial units. The bioassays used in this study were the Ames Salmonella plate incorporation test for mutagenicity and the rabbit alveolar macrophage (RAM) system for cytotoxicity.
- Research Organization:
- Health Effects Research Lab., Research Triangle Park, NC (USA)
- OSTI ID:
- 5504409
- Report Number(s):
- PB-83-243246; EPA-600-D-83-061
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOL WASTES
ASHES
BIOASSAY
CARBONACEOUS MATERIALS
CHEMICAL REACTIONS
COAL
COMBUSTION
ENERGY SOURCES
FLUIDIZED-BED COMBUSTION
FLY ASH
FOSSIL FUELS
FUELS
MATERIALS
MUTAGEN SCREENING
OXIDATION
RESIDUES
SAMPLE PREPARATION
SAMPLING
SCREENING
THERMOCHEMICAL PROCESSES
TOXICITY
WASTES