Benzodiazepine receptor binding in vivo with (/sup 3/)-Ro 15-1788
Journal Article
·
· Life Sci.; (United States)
In vivo benzodiazepine receptor binding has generally been studied by ex vivo techniques. In this investigation, the authors identify the conditions where (/sup 3/H)-Ro 15-1788 labels benzodiazepine receptors by true in vivo binding, i.e. where workable specific to nonspecific ratios are obtained in intact tissues without homogenization or washing. (/sup 3/H)-Flunitrazepam and (/sup 3/H)-clonazepam did not exhibit useful in vivo receptor binding. 39 references, 5 figures, 1 table.
- Research Organization:
- Johns Hopkins Univ. School of Medicine, Baltimore, MD
- OSTI ID:
- 5520821
- Journal Information:
- Life Sci.; (United States), Journal Name: Life Sci.; (United States) Vol. 37:4; ISSN LIFSA
- Country of Publication:
- United States
- Language:
- English
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