Chromogranin A is present in and released by fish endocrine tissue

Journal Article · Mon Jun 01 04:00:00 EDT 1987 · Life Sci.; (United States)

DOI:https://doi.org/10.1016/0024-3205(87)90002-6· OSTI ID:5520618

Deftos, L J; Bjoernsson, B T; Burton, D W; O'Connor, D T; Copp, D H

Chromogranin A (CgA) is a protein that is present in many mammalian endocrine cells and co-secreted with their resident hormones. The authors have demonstrated the presence of CgA by immunohistology in the ultimobranchial glands and corpuscles of Stannius of rainbow trout. CgA was also detected by radioimmunoassay in the medium of incubated coho salmon ultimobranchial glands. Their observations demonstrate the presence of CgA in endocrine glands of evolutionarily divergent species. These observations are consistent with the hypothesis that CgA participates in the secretory process of a wide variety of hormones. 18 references, 1 figure, 1 table.

• Research Organization: Univ. of California, San Diego
• OSTI ID: 5520618
• Journal Information: Life Sci.; (United States), Journal Name: Life Sci.; (United States) Vol. 40:22; ISSN LIFSA
• Country of Publication: United States
• Language: English

Related Subjects

550201* -- Biochemistry-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ANIMALS
AQUATIC ORGANISMS
BODY
ENDOCRINE GLANDS
FISHES
GLANDS
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
ORGANIC COMPOUNDS
ORGANS
PROTEINS
RADIOASSAY
RADIOIMMUNOASSAY
RADIOIMMUNOLOGY
SECRETION
TRACER TECHNIQUES
TROUT
VERTEBRATES