Relationship between radiation dosage, dose rate and number of aberrant anaphases in fish embryos

Journal Article · Thu Mar 01 04:00:00 EST 1979 · Radiobiology (USSR) (Engl. Transl.); (United States)

OSTI ID:5511531

Pechkurenkov, V L

Previous studies have shown that the yield of aberrant anaphases in fish embryos is determined more by dose rate than dosage and that a significant part of chromosomal lesions in embryos may exist to the end of gastrulation in discrete form and expressed as aberrations only in the course of organogenesis, after several cell cycles, in the case of exposure of developing fish roe to chronic ..gamma..-radiation at the organogenetic stages. Experiments with loach roe developing in a /sup 89/Sr solution with activity of 1 x 10/sup -2/ Ci/l revealed that there is an increase in chromosomal aberrations in embryos at the stage of organogenesis that begins at least 5 to 6 h after the embryos were placed in the radionuclide solution. But this could have occurred because accretion of radionuclide by loach roe lasts about 3 to 4 h up to saturation; i.e., irradiation of the roe for these 5 h occurs at a variable dose rate. The experiment described here was conducted to determine the duration of the latency period of formation of chromosomal aberrations and time at which a stable level of aberrant anaphases is reached in the case of exposure to chronic radiation at a constant dose rate.

• Research Organization: All-Union Scientific Research Inst. of Pond Fisheries, Moscow, USSR
• OSTI ID: 5511531
• Journal Information: Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 1 :4; ISSN RADBA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALINE EARTH ISOTOPES
ANIMALS
AQUATIC ORGANISMS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CELL DIVISION
CHROMOSOMAL ABERRATIONS
CHRONIC EXPOSURE
CHRONIC IRRADIATION
DATA
DATA FORMS
DAYS LIVING RADIOISOTOPES
DOSE RATES
DOSE-RESPONSE RELATIONSHIPS
DOSES
ELECTROMAGNETIC RADIATION
EMBRYOS
EVEN-ODD NUCLEI
EXPERIMENTAL DATA
FISHES
GAMMA RADIATION
INFORMATION
INTERMEDIATE MASS NUCLEI
IONIZING RADIATIONS
IRRADIATION
ISOTOPES
MITOSIS
MUTATIONS
NUCLEI
NUMERICAL DATA
ONTOGENESIS
ORGANS
RADIATION DOSES
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
STRONTIUM 89
STRONTIUM ISOTOPES
TABLES
VERTEBRATES