Differential effects of chronic lead intoxication on circadian rhythm of ambulatory activity and on regional brain norepinephrine levels in rats
Journal Article
·
· Bull. Environ. Contam. Toxicol.; (United States)
Changes in biochemical mechanisms and amine concentrations in the brain have been manifested in the form of varying disorders and abnormalities in behavior, including motor-activity, which has been proved with a number of psychoactive drugs. It has been reported that increased level of cerebral norepinephrine (NE) has been shown to be associated with motor hyper-activity, and in lead exposed rats. No study is available which could account for the pattern of changes in spontaneous ambulatory responses in an open field situation together with the steady state regional levels of NE in the brain of chronically lead exposed rats. Therefore, it seemed to be worthwhile to study the circadian rhythm of ambulatory activity and its association with NE levels in various brain regions of rats exposed to lead.
- Research Organization:
- Aligarh Muslim Univ., India
- OSTI ID:
- 5487873
- Journal Information:
- Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 36:1; ISSN BECTA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Waterborne lead affects circadian variations of brain neurotransmitters in fathead minnows
cap alpha. -Methyl-p-tyrosine shifts circadian temperature rhythms
Effects of chronic exposure to cadmium, lead, and mercury on brain
Journal Article
·
Fri Sep 01 00:00:00 EDT 1995
· Bulletin of Environmental Contamination and Toxicology
·
OSTI ID:93927
cap alpha. -Methyl-p-tyrosine shifts circadian temperature rhythms
Journal Article
·
Wed Sep 01 00:00:00 EDT 1982
· Am. J. Physiol.; (United States)
·
OSTI ID:6324259
Effects of chronic exposure to cadmium, lead, and mercury on brain
Journal Article
·
Sun Oct 31 23:00:00 EST 1976
· Res. Commun. Chem. Pathol. Pharmacol.; (United States)
·
OSTI ID:7254554
Related Subjects
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION SPECTROSCOPY
ADRENAL HORMONES
ANIMALS
AUTONOMIC NERVOUS SYSTEM AGENTS
BEHAVIOR
BIOCHEMISTRY
BODY
BRAIN
CARDIOTONICS
CARDIOVASCULAR AGENTS
CENTRAL NERVOUS SYSTEM
CHEMISTRY
CHRONIC EXPOSURE
DAILY VARIATIONS
DATA
DRUGS
ELEMENTS
EXPERIMENTAL DATA
HORMONES
INFORMATION
LEAD
MAMMALS
METALS
NERVOUS SYSTEM
NEUROREGULATORS
NORADRENALINE
NUMERICAL DATA
ORGANS
RATS
RODENTS
SPECTROSCOPY
STEROID HORMONES
SYMPATHOMIMETICS
VARIATIONS
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION SPECTROSCOPY
ADRENAL HORMONES
ANIMALS
AUTONOMIC NERVOUS SYSTEM AGENTS
BEHAVIOR
BIOCHEMISTRY
BODY
BRAIN
CARDIOTONICS
CARDIOVASCULAR AGENTS
CENTRAL NERVOUS SYSTEM
CHEMISTRY
CHRONIC EXPOSURE
DAILY VARIATIONS
DATA
DRUGS
ELEMENTS
EXPERIMENTAL DATA
HORMONES
INFORMATION
LEAD
MAMMALS
METALS
NERVOUS SYSTEM
NEUROREGULATORS
NORADRENALINE
NUMERICAL DATA
ORGANS
RATS
RODENTS
SPECTROSCOPY
STEROID HORMONES
SYMPATHOMIMETICS
VARIATIONS
VERTEBRATES