Acute selenite toxicosis in lambs

Journal Article · Mon Jan 01 04:00:00 EST 1968 · J. Am. Vet. Med. Assoc.; (United States)

OSTI ID:5482873

Morrow, D A

Acute toxicosis occurred in 20 young lambs treated with sodium selenite to prevent nutritional muscular dystrophy. Similar toxicosis occurred in an experimentally poisoned ewe. The lambs were given 10 mg. of sodium selenite orally. Seven died within 10 to 16 hours. In 8 others, diarrhea developed but they recovered; the other 5 apparently were unaffected. The clinical signs in the experimentally poisoned ewe were depression, ataxia, dyspnea, frequent urination, elevated temperature, and increased pulse and respiratory rates. Terminal signs included cyanotic mucous membranes, dilated pupils, tympany, and recumbency. Gross and microscopic pathologic changes occurred in the respiratory, circulatory, digestive, and urinary systems. The changes included edema, hyperemia, hemorrhages, necrosis, and degeneration of these organ systems. A toxicologic analysis of the liver and kidneys indicated presence of toxic amounts of sodium selenite. Since there was no treatment known for acute sodium selenite toxicosis, none was given. 17 references, 1 figure.

• Research Organization: New York State Veterinary College, Ithaca
• OSTI ID: 5482873
• Journal Information: J. Am. Vet. Med. Assoc.; (United States), Journal Name: J. Am. Vet. Med. Assoc.; (United States) Vol. 152; ISSN JAVMA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
CARDIOVASCULAR SYSTEM
DATA
DATA COMPILATION
DEATH
DIGESTIVE SYSTEM
DOMESTIC ANIMALS
EDEMA
GASTROINTESTINAL TRACT
INFORMATION
MAMMALS
NECROSIS
NUMERICAL DATA
PATHOLOGICAL CHANGES
RESPIRATORY SYSTEM
RUMINANTS
SELENIUM COMPOUNDS
SHEEP
SYMPTOMS
TOXICITY
VERTEBRATES