Development of a screening procedure for use in the evaluation of topical protectants after challenge with vesicating agents. Technical report

Technical Report · Sun Mar 31 23:00:00 EST 1991

OSTI ID:5459281

Forster, J S; Jacinto, B; Gadson, C; Mershon, M M

1,1{prime} -Thiobis2-chloroethane (bis(2-chloroethyl)sulfide, sulfur mustard, H) causes skin, respiratory and eye injury land has been identified as being mutagenic and carcinogenic. The development of topical protectants that can decrease the effects of cutaneous exposure to vesicating chemical warfare agents or that may enhance the effectiveness of decontamination through limiting penetration to the skin should significantly enhance a soldier's ability to carry out his or her job in a chemically hostile environment. Preliminary in vivo studies with a small number of candidate topical protectants demonstrated that they could provide protection against several different chemical agents.

• Research Organization: Army Medical Research Inst. of Chemical Defense, Aberdeen Proving Ground, MD (United States)
• OSTI ID: 5459281
• Report Number(s): AD-A-234947/0/XAB; USAMRICD-TR--91-06
• Country of Publication: United States
• Language: English

Related Subjects

45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEFENSE
450600* -- Military Technology
Weaponry
& National Defense-- Chemical & Biological-- (1990)
ABSORPTION
CARCINOGENS
CHEMICAL WARFARE AGENTS
CLEANING
COATINGS
DECONTAMINATION
DISEASES
ELEMENTS
IN VIVO
MITIGATION
MUTAGENS
NONMETALS
PERFORMANCE TESTING
PROTECTIVE COATINGS
RESPIRATORY SYSTEM
SKIN ABSORPTION
SKIN DISEASES
SULFUR
TESTING
UPTAKE
WEAPONS