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Effect of exercise and feed restriction on body weight and lipogenesis in the male Wistar rat

Conference · · Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States)
OSTI ID:5450193
Male Wistar rats were swum for either 1.5 or 3.0 hours per day from 6 through 32 weeks of age. At 32 weeks of age, the rats were injected intraperitoneally with /sup 3/H/sub 2/O and sacrificed 1 hour later. Liver activities of glucose-6-phosphate dehydrogenase (G6PD) and malic enzyme (MF) were also measured. Feed intakes of exercised rats were slightly higher, whereas their body weights were slightly lower when compared to those of non-exercised ad libitum-fed rats (controls). Liver ME and G6PD activities of exercised rats were 30% and 50% higher, respectively, than those of control rats. Non-exercised rats, whose body weights were controlled by feed restriction to match those of exercised rats, also showed increases in liver ME and G6PD activities (30%). The relationship between rates of incorporation of /sup 3/H/sub 2/O into liver fat and activities of liver ME and G6PD as affected by exercise and feed restriction will be discussed.
Research Organization:
Univ. of Tennessee, Knoxville
OSTI ID:
5450193
Report Number(s):
CONF-8604222-
Conference Information:
Journal Name: Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States) Journal Volume: 45:3
Country of Publication:
United States
Language:
English