Third chronological supplement to the Carcinogenic Potency Database: Standardized results of animal bioassays published through December 1986 and by the National Toxicology Program through June 1987

Journal Article · Thu Mar 01 04:00:00 EST 1990 · Environmental Health Perspectives; (United States)

DOI:https://doi.org/10.1289/ehp.9084215· OSTI ID:5447575

Gold, L S; Slone, T H; Backman, G M; Eisenberg, S; Da Costa, M; Wong, M; Manley, N B; Rohrbach, L ^[1]; Ames, B N ^[2]

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1. Lawrence Berkeley Laboratory, CA (USA)
2. Univ. of California, Berkeley (USA)

This paper is the third chronological supplement to the Carcinogenic Potency Database that first appeared in this journal in 1984 (1-4). The authors report here results of carcinogenesis bioassays published in the general literature between January 1985 and December 1986, and in Technical Reports of the National Toxicology Program between June 1986 and June 1987. This supplement includes results of 337 long-term, chronic experiments of 121 compounds, and reports the same information about each experiment in the same plot format as the earlier papers. The reader needs to refer to the 1984 publication for a guide to the plot of the database, a complete description of the numerical index of carcinogenic potency, and a discussion of the sources of data, the rationale for the inclusion of particular experiments and particular target sites, and the conventions adopted in summarizing the literature. The four plots of the database are to be used together as results published earlier are not repeated. In all, the four plots include results for approximately 4,000 experiments on 1,050 chemicals. Appendix 14 of this paper is an alphabetical index to all chemicals in the database and indicates which plot(s) each chemical appears in. A combined plot of all results from the four separate papers, that is ordered alphabetically by chemical, is available from the first author, in printed form or on computer tape or diskette.

• DOE Contract Number: AC03-76SF00098
• OSTI ID: 5447575
• Journal Information: Environmental Health Perspectives; (United States), Journal Name: Environmental Health Perspectives; (United States) Vol. 84; ISSN 0091-6765; ISSN EVHPA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACETALDEHYDE
ACETYLAMINOFLUORENES
ACRYLAMIDE
ALDEHYDES
AMIDES
AMINES
ANIMALS
ANTI-INFECTIVE AGENTS
ANTIBIOTICS
AROMATICS
BIOASSAY
CARCINOGEN SCREENING
CARCINOGENESIS
DRUGS
HYDROCARBONS
MAMMALS
NITRO COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PATHOGENESIS
POLYCYCLIC AROMATIC AMINES
POLYCYCLIC AROMATIC HYDROCARBONS
POLYCYCLIC NITRO COMPOUNDS
RODENTS
SCREENING
VERTEBRATES