Radiologic findings in late-onset systemic lupus erythematosus
Systemic lupus erythematosus in the elderly has a different clinical and serologic course from that in young patients. Radiographic findings in patients in whom the diagnosis was made after age 50 were compared with findings in younger patients to see if the radiologic patterns are also different. The only significant radiographic difference between the two groups was that the older group had a greater incidence of soft-tissue swelling of the hands and wrists (p < 0.001). There was no significant difference in osteopenia, erosion, soft-tissue calcification, alignment abnormalities, or intrathoracic findings. Of 24 patients over age 50, two developed lymphoma and another developed multiple myeloma. The data agree with clinical observations that there is a higher incidence of arthritis in late-onset lupus, but clinical findings of increased incidence of pleuropericardial disease are not confirmed radiographically. The coincidence of hematologic malignancy with late-onset lupus in this series is noteworthy.
- Research Organization:
- Harvard Medical School, Boston, MA
- OSTI ID:
- 5441164
- Journal Information:
- AJR, Am. J. Roentgenol.; (United States), Journal Name: AJR, Am. J. Roentgenol.; (United States) Vol. 140:3; ISSN AAJRD
- Country of Publication:
- United States
- Language:
- English
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550900 -- Pathology
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ADULTS
AGE GROUPS
BACTERIAL DISEASES
BIOMEDICAL RADIOGRAPHY
BODY
BODY AREAS
BONE JOINTS
CHEST
CORRELATIONS
DIAGNOSTIC TECHNIQUES
DISEASES
ELDERLY PEOPLE
HEMIC DISEASES
HUMAN POPULATIONS
INFECTIOUS DISEASES
LUPUS
MEDICINE
MINORITY GROUPS
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATHOLOGY
PATIENTS
POPULATIONS
RADIOLOGY
SKELETON
SKIN DISEASES
TUBERCULOSIS