Occupational intoxication and long-term persistence of phencyclidine (PCP) in law enforcement personnel
Journal Article
·
· Clin. Toxicol.; (United States)
By utilizing a glass capillary gas chromatographic nitrogen detector (GC2-N) method specific for phencyclidine (PCP) and sensitive to pg/mL in blood or urine samples, we have demonstrated occupational intoxication of law enforcement personnel charged with handling confiscated illegal PCP preparations. Further, we have demonstrated persistence of PCP in blood and urine for at least 6 months after the last known occupational exposure in one officer. Some aspects of the PCP problem are outlined, and possible mechanisms of the occupational intoxication are discussed.
- Research Organization:
- Department of Psychiatry, University of Southern California School of Medicine, Los Angeles
- OSTI ID:
- 5439581
- Journal Information:
- Clin. Toxicol.; (United States), Vol. 18:9
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
ENFORCEMENT
OCCUPATIONAL SAFETY
PIPERIDINES
METABOLISM
ANESTHETICS
BLOOD
LAWS
PERSONNEL
QUANTITATIVE CHEMICAL ANALYSIS
URINE
AMINES
AZINES
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY FLUIDS
CENTRAL NERVOUS SYSTEM DEPRESSANTS
CHEMICAL ANALYSIS
DRUGS
HETEROCYCLIC COMPOUNDS
MATERIALS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PYRIDINES
SAFETY
WASTES
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
550200 - Biochemistry
59 BASIC BIOLOGICAL SCIENCES
ENFORCEMENT
OCCUPATIONAL SAFETY
PIPERIDINES
METABOLISM
ANESTHETICS
BLOOD
LAWS
PERSONNEL
QUANTITATIVE CHEMICAL ANALYSIS
URINE
AMINES
AZINES
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY FLUIDS
CENTRAL NERVOUS SYSTEM DEPRESSANTS
CHEMICAL ANALYSIS
DRUGS
HETEROCYCLIC COMPOUNDS
MATERIALS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PYRIDINES
SAFETY
WASTES
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
550200 - Biochemistry