Effect of chemical modification on enzymatic activities and stabilities
Journal Article
·
· Biotechnol. Bioeng.; (United States)
The influence of chemical modification on the initial specific activity, residual activity, and deactivation kinetics of various enzymes is analyzed using a series mechanism. This straightforward multistate sequential model presented is consistent with the enzyme deactivation data obtained from different fields. The enzymes are placed in five different categories depending on the effect of chemical modification on initial specific activity and residual activity or stability. Wherever possible, structure-function relationships are described for the enzymes in the different categories. The categorization provides one avenue that leads to further physical insights into enzyme deactivation processes and into the enzyme structure itself. 69 references.
- Research Organization:
- Univ. of Mississippi, University
- OSTI ID:
- 5439258
- Journal Information:
- Biotechnol. Bioeng.; (United States), Journal Name: Biotechnol. Bioeng.; (United States) Vol. 28:2; ISSN BIBIA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
09 BIOMASS FUELS
090222* -- Alcohol Fuels-- Preparation from Wastes or Biomass-- (1976-1989)
140504 -- Solar Energy Conversion-- Biomass Production & Conversion-- (-1989)
CHEMICAL REACTION KINETICS
CHEMICAL REACTIONS
CHEMISTRY
DEACTIVATION
DECOMPOSITION
ENZYMATIC HYDROLYSIS
ENZYME ACTIVITY
ENZYMES
HYDROLYSIS
KINETICS
LYSIS
MATHEMATICAL MODELS
MODIFICATIONS
MOLECULAR STRUCTURE
REACTION KINETICS
SOLVOLYSIS
STABILITY
STRUCTURAL CHEMICAL ANALYSIS
090222* -- Alcohol Fuels-- Preparation from Wastes or Biomass-- (1976-1989)
140504 -- Solar Energy Conversion-- Biomass Production & Conversion-- (-1989)
CHEMICAL REACTION KINETICS
CHEMICAL REACTIONS
CHEMISTRY
DEACTIVATION
DECOMPOSITION
ENZYMATIC HYDROLYSIS
ENZYME ACTIVITY
ENZYMES
HYDROLYSIS
KINETICS
LYSIS
MATHEMATICAL MODELS
MODIFICATIONS
MOLECULAR STRUCTURE
REACTION KINETICS
SOLVOLYSIS
STABILITY
STRUCTURAL CHEMICAL ANALYSIS