Enhancement of survival of CHO cells by acidic pH after X irradiation
Journal Article
·
· Radiat. Res.; (United States)
Asynchronous Chinese hamster ovary cells were incubated in medium that was acidic (pH 6.70) before, during and/or after X irradiation (13 Gy). A two- to threefold increase in survival (from 7.1 X 10/sup -4/) was observed when the postirradiation medium was acidic. Incubation in acidic medium either before or during irradiation did not enhance survival. This increase in survival must be due to either a decrease in fixation of damage or to an increase in recovery from damage.
- Research Organization:
- Colorado State Univ., Fort Collins
- OSTI ID:
- 5430990
- Journal Information:
- Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 89:2; ISSN RAREA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560111* -- Radiation Effects on Biochemicals-- In Vitro-- (-1987)
560114 -- Radiation Effects on Biochemicals-- In Animals-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
ELECTROMAGNETIC RADIATION
FEMALE GENITALS
GONADS
HAMSTERS
INJURIES
IONIZING RADIATIONS
MAMMALS
MORTALITY
ORGANS
OVARIES
PH VALUE
RADIATION EFFECTS
RADIATION INJURIES
RADIATIONS
RADIOSENSITIVITY EFFECTS
RESPONSE MODIFYING FACTORS
RODENTS
VERTEBRATES
X RADIATION
560114 -- Radiation Effects on Biochemicals-- In Animals-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
ELECTROMAGNETIC RADIATION
FEMALE GENITALS
GONADS
HAMSTERS
INJURIES
IONIZING RADIATIONS
MAMMALS
MORTALITY
ORGANS
OVARIES
PH VALUE
RADIATION EFFECTS
RADIATION INJURIES
RADIATIONS
RADIOSENSITIVITY EFFECTS
RESPONSE MODIFYING FACTORS
RODENTS
VERTEBRATES
X RADIATION