Trace element analysis of biological materials: Complementarity of PIXE and NAA
Some 26 of the 90 naturally occurring elements are generally regarded to be essential for animal life. Of those, 15 are referred to as trace elements, i.e. F,Si, V,Cr,Mn,Fe,Co,Ni,Cu,Zn,As,Se,Mo,Sn and I. In addition to the essential elements, many more trace elements are observed in living tissues. They include Al,Ti,Br,Rb, Cd,Sb,Cs,Au,Hg,Pb and others. Some of these elements (e.g. Cd,Hg,Pb) are often included in multi-element measurements because of their known toxicity, while others (e.g. Br,Rb) are of interest because they may replace essential elements under certain conditions and eventually become regarded as essential elements as well. By combining PIXE and NAA more trace elements can be determined in biological materials than by any of the two techniques alone. This is demonstrated in applications to serum and serum albumin samples and in a study of trace elements in tumor and lung tissues, collected from mice injected with B-16 melanoma tumor cells.
- Research Organization:
- Instituut voor Nucleaire Wetenschappen, Rijksuniversiteit Gent, Proeftuinstraat 86, B-9000 Gent
- OSTI ID:
- 5415365
- Report Number(s):
- CONF-801111-
- Journal Information:
- IEEE Trans. Nucl. Sci.; (United States), Journal Name: IEEE Trans. Nucl. Sci.; (United States) Vol. NS-28:2; ISSN IETNA
- Country of Publication:
- United States
- Language:
- English
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400101* -- Activation
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Radiometric & Radiochemical Procedures
400103 -- Radiometric & Radiochemical Procedures-- (-1987)
ACTIVATION ANALYSIS
ALBUMINS
ALKALI METALS
ALUMINIUM
ANIMAL CELLS
ANTIMONY
ARSENIC
BARYON REACTIONS
BIOLOGICAL MATERIALS
BLOOD SERUM
BODY
BROMINE
CADMIUM
CESIUM
CHEMICAL ANALYSIS
CHROMIUM
COBALT
COMPARATIVE EVALUATIONS
COPPER
ELEMENTS
FLUORINE
GOLD
HADRON REACTIONS
HALOGENS
IODINE
IRON
LEAD
LUNGS
MANGANESE
MATERIALS
MERCURY
METALS
MOLYBDENUM
NEUTRON REACTIONS
NICKEL
NONDESTRUCTIVE ANALYSIS
NONMETALS
NUCLEAR REACTIONS
NUCLEON REACTIONS
ORGANIC COMPOUNDS
ORGANS
PIXE ANALYSIS
PROTEINS
RESPIRATORY SYSTEM
RUBIDIUM
SAMPLING
SELENIUM
SEMIMETALS
SILICON
TIN
TITANIUM
TRACE AMOUNTS
TRANSITION ELEMENTS
TUMOR CELLS
VANADIUM
X-RAY EMISSION ANALYSIS
ZINC