PCBs, PCQs and PCDFs in tissues of Yusho and Yu-Cheng patients

Journal Article · Fri Feb 01 04:00:00 EST 1985 · Environ. Health Perspect.; (United States)

DOI:https://doi.org/10.2307/3429876· OSTI ID:5414422

Miyata, H; Fukushima, S; Kashimoto, T; Kunita, N

All five samples of oil involved in the recent Yu-Cheng outbreak were heavily contaminated with PCBs, PCQs and PCDFs at levels, on the average, of 62, 20 and 0.14 ppm, respectively. The samples not only had roughly one-tenth of the contamination by PCBs, PCQs and PCDFs but also three to four times lower ratios of PCQs and PCDFs to PCBs than samples of oil involved in Yusho in Japan. PCBs, PCQs and PCDFs present were all composed of similar congeners to the ones found in the Yusho specimens, though some variation of the component ratios of PCBs and PCDFs were observed. On the other hand, five patients with Yusho who died 1 to 10 years following poisoning had markedly higher tissue levels of PCDFs and PCQs than did a worker occupationally exposed to PCBs. Taking great differences in the process of the healing and the tissue levels of PCBs, PCQs and PCDFs between the two poisoning cases into consideration, PCDFs and PCQs - especially the former - and not PCBs are deduced to be strongly associated with the development of Yusho.

• Research Organization: Osaka Prefectural Institute of Public Health, Japan
• OSTI ID: 5414422
• Journal Information: Environ. Health Perspect.; (United States), Journal Name: Environ. Health Perspect.; (United States) Vol. 59; ISSN EVHPA
• Country of Publication: United States
• Language: English

Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADIPOSE TISSUE
ANIMAL TISSUES
AROMATICS
ASIA
BENZOFURANS
BIOLOGICAL MATERIALS
BLOOD
BODY
BODY FLUIDS
CHEMICAL ANALYSIS
CHLORINATED AROMATIC HYDROCARBONS
CONNECTIVE TISSUE
DIGESTIVE SYSTEM
DISTRIBUTION
FURANS
GLANDS
HALOGENATED AROMATIC HYDROCARBONS
HETEROCYCLIC COMPOUNDS
HYDROCARBONS
ISLANDS
JAPAN
LIVER
MATERIALS
OILS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANS
OTHER ORGANIC COMPOUNDS
PATIENTS
QUATERPHENYLS
TAIWAN
TISSUE DISTRIBUTION
TISSUES
VEGETABLE OILS