Angina and exertional myocardial ischemia in diabetic and nondiabetic patients: assessment by exercise thallium scintigraphy

Journal Article · Mon Feb 01 04:00:00 EST 1988 · Ann. Intern. Med.; (United States)

DOI:https://doi.org/10.7326/0003-4819-108-2-170· OSTI ID:5408467

Nesto, R W; Phillips, R T; Kett, K G; Hill, T; Perper, E; Young, E; Leland, Jr, O S

Patients with diabetes mellitus and coronary artery disease are thought to have painless myocardial ischemia more often than patients without diabetes. We studied 50 consecutive patients with diabetes and 50 consecutive patients without diabetes, all with ischemia, on exercise thallium scintigraphy to show the reliability of angina as a marker for exertional ischemia. The two groups had similar clinical characteristics, treadmill test results, and extent of infarction and ischemia, but only 7 patients with diabetes compared with 17 patients without diabetes had angina during exertional ischemia. In diabetic patients the extent of retinopathy, nephropathy, or peripheral neuropathy was similar in patients with and without angina. Angina is an unreliable index of myocardial ischemia in diabetic patients with coronary artery disease. Given the increased cardiac morbidity and mortality in such patients, periodic objective assessments of the extent of ischemia are warranted.

• Research Organization: New England Deaconess Hospital, Boston, MA (USA)
• OSTI ID: 5408467
• Journal Information: Ann. Intern. Med.; (United States), Journal Name: Ann. Intern. Med.; (United States) Vol. 108:2; ISSN AIMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DIABETES MELLITUS
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ENDOCRINE DISEASES
EXERCISE
HEART
ISCHEMIA
ISOTOPES
METABOLIC DISEASES
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
SCINTISCANNING
THALLIUM ISOTOPES
VASCULAR DISEASES