Multidimensional packed capillary coupled to open tubular column supercritical fluid chromatography using a valve-switching interface

Journal Article · Sun Jul 15 04:00:00 EDT 1990 · Analytical Chemistry (Washington); (United States)

DOI:https://doi.org/10.1021/ac00213a007· OSTI ID:5408355

Juvancz, Z; Payne, K M; Markides, K E; Lee, M L ^[1]

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1. Brigham Young Univ., Provo (USA)

An on-line two-dimensional supercritical fluid chromatographic system (SFC/SFC) was constructed by utilizing a rotary valve interface to provide independent flow control of the two dimensions. A cold trap was employed to refocus solutes from single or multiple fractional cuts, after being transferred to the second dimension. Improved performance, including time savings, was achieved with a packed capillary to open tubular column arrangement and two independently controlled pumps, compared to earlier reported single-pump open tubular column SFC/SFC and packed capillary column SFC/SFC systems. The packed capillary in the first dimension provided a rapid chemical class separation, while the open tubular column in the second dimension provided high resolution of closely related isomers.

• OSTI ID: 5408355
• Journal Information: Analytical Chemistry (Washington); (United States), Journal Name: Analytical Chemistry (Washington); (United States) Vol. 62:14; ISSN 0003-2700; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
CHROMATOGRAPHY
COLD TRAPS
COLUMN PACKING
CONDENSERS
EXTRACTION APPARATUSES
EXTRACTION COLUMNS
MEASURING INSTRUMENTS
MEASURING METHODS
PACKINGS
PERFORMANCE
SEPARATION EQUIPMENT
SEPARATION PROCESSES
SUPERCRITICAL FLUID CHROMATOGRAPHY
TRAPS
VAPOR CONDENSERS