Multidimensional packed capillary coupled to open tubular column supercritical fluid chromatography using a valve-switching interface

Journal Article · Sun Jul 15 00:00:00 EDT 1990 · Analytical Chemistry (Washington); (United States)

DOI:https://doi.org/10.1021/ac00213a007· OSTI ID:5408355

Juvancz, Z; Payne, K M; Markides, K E; Lee, M L ^[1]

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1. Brigham Young Univ., Provo (USA)

An on-line two-dimensional supercritical fluid chromatographic system (SFC/SFC) was constructed by utilizing a rotary valve interface to provide independent flow control of the two dimensions. A cold trap was employed to refocus solutes from single or multiple fractional cuts, after being transferred to the second dimension. Improved performance, including time savings, was achieved with a packed capillary to open tubular column arrangement and two independently controlled pumps, compared to earlier reported single-pump open tubular column SFC/SFC and packed capillary column SFC/SFC systems. The packed capillary in the first dimension provided a rapid chemical class separation, while the open tubular column in the second dimension provided high resolution of closely related isomers.

• OSTI ID: 5408355
• Journal Information: Analytical Chemistry (Washington); (United States), Vol. 62:14; ISSN 0003-2700
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
SUPERCRITICAL FLUID CHROMATOGRAPHY
MEASURING METHODS
COLD TRAPS
COLUMN PACKING
EXTRACTION COLUMNS
MEASURING INSTRUMENTS
PERFORMANCE
CHROMATOGRAPHY
CONDENSERS
EXTRACTION APPARATUSES
PACKINGS
SEPARATION EQUIPMENT
SEPARATION PROCESSES
TRAPS
VAPOR CONDENSERS
400102* - Chemical & Spectral Procedures