Intravenous vs. left ventricular injection of ionic contrast material: hemodynamic implications for digital subtraction angiography

Journal Article · Tue Mar 01 04:00:00 EST 1983 · AJR, Am. J. Roentgenol.; (United States)

DOI:https://doi.org/10.2214/ajr.140.3.425· OSTI ID:5404699

Mancini, G B ^[1]; Ostrander, D R; Slutsky, R A; Shabetai, R; Higgins, C B

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1. Univ. of California School of Medicine, San Diego

Because of the increased use of intravenous injection of contrast material for the evaluation of cardiac structure and function by digital subtraction techniques, a study was done to assess the hemodynamic effects of contrast material when used in this fashion in man. In 10 patients, with each serving as his own control, the effects of intravenous and intraventricular injections of sodium meglumine diatrizoate (Renografin 76) in the same dose were compared. There was no difference between these two methods with respect to changes in pulmonary wedge pressures, systemic pressures, and pulmonary vascular resistance. The elevation of mean pulmonary artery and right atrial pressure was greater after the intraventricular injection (p <0.05). The elevated cardiac output and systemic vascular resistance returned to control values somewhat more quickly after the intravenous injection (p<0.001 and p<0.05, respectively); and the increase in cardiac output was greater after the intravenous injection at 1 min (p<0.05), but less than after the intraventricular injection at 2 min (p<0.05). Despite the detection of these statistically significant differences, the magnitude and timing of these differences are too small to justify the notion that imaging by intravenous injections of standard ionic contrast media provides any substantial hemodynamic benefits or decreased risk to the patient.

• OSTI ID: 5404699
• Journal Information: AJR, Am. J. Roentgenol.; (United States), Journal Name: AJR, Am. J. Roentgenol.; (United States) Vol. 140:3; ISSN AAJRD
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOMEDICAL RADIOGRAPHY
BLOOD PRESSURE
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
CONTRAST MEDIA
DATA
DIAGNOSTIC TECHNIQUES
EXPERIMENTAL DATA
INFORMATION
INJECTION
INTAKE
INTRAVENOUS INJECTION
MEDICINE
NUCLEAR MEDICINE
NUMERICAL DATA
ORGANS
RADIOLOGY