Early and late effects in mouse lung and rectum

Journal Article · Wed Dec 01 04:00:00 EST 1982 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(82)90550-8· OSTI ID:5403524

Fowler, J F ^[1]; Parkins, C S; Denekamp, J; Terry, N H.A.; Maughan, R L; Travis, E L

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1. Mount Veron Hospital, Northwood, England

No higher RBE's were found for late than for early damage in mouse rectum up to 70 weeks or mouse lungs up to 48 weeks after irradiation with 3.0 MeV neutrons (4MeV deuterons on Be). The smallest neutron doses per fraction were 1.5 and 0.6 Gy for rectal and lung irradiation, respectively. There was a suggestion of higher late RBE's for small doses per fraction in the lung. Slow repair after 2 neutron doses split by 31 days was unequivocally demonstrated in the lung, of magnitude about 1 Gy, possibly decreasing after about 40 weeks.

• OSTI ID: 5403524
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 8:12; ISSN IOBPD
• Country of Publication: United States
• Language: English

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560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METAL ISOTOPES
ANIMALS
BARYONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
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DELAYED RADIATION EFFECTS
DIGESTIVE SYSTEM
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ELEMENTARY PARTICLES
FAST NEUTRONS
FERMIONS
FRACTIONATED IRRADIATION
GAMMA RADIATION
GASTROINTESTINAL TRACT
HADRONS
INTESTINES
IONIZING RADIATIONS
IRRADIATION
ISOTOPES
LARGE INTESTINE
LUNGS
MAMMALS
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ODD-EVEN NUCLEI
ORGANS
RADIATION EFFECTS
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RESPIRATORY SYSTEM
RODENTS
VERTEBRATES
X RADIATION
YEARS LIVING RADIOISOTOPES