Early and late effects in mouse lung and rectum

Journal Article · Wed Dec 01 04:00:00 EST 1982 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(82)90550-8· OSTI ID:5239060

Fowler, J F ^[1]; Parkins, C S; Denekamp, J; Terry, N H.A.; Maughan, R L; Travis, E L

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1. Mount Vernon Hospital, Northwood, England

No higher RBE's were found for late than for early damage in mouse rectum up to 70 weeks or mouse lungs up to 48 weeks after irradiation with 3.0 MeV neutrons (4 MeV deuterons on Be). The smallest neutron doses per fraction were 1.5 and 0.6 Gy for rectal and lung irradiation, respectively. There was a suggestion of higher late RBE's for small doses per fraction in the lung. Slow repair after 2 neutron doses split by 31 days was unequivocally demonstrated in the lung, of magnitude about 1 Gy, possibly decreasing after about 40 weeks.

• OSTI ID: 5239060
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 8:12; ISSN IOBPD
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METAL ISOTOPES
ANIMALS
BARYONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
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CESIUM 137
CESIUM ISOTOPES
DELAYED RADIATION EFFECTS
DIGESTIVE SYSTEM
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ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
FAST NEUTRONS
FERMIONS
FRACTIONATED IRRADIATION
GAMMA RADIATION
GASTROINTESTINAL TRACT
HADRONS
INTESTINES
IONIZING RADIATIONS
IRRADIATION
ISOTOPES
LARGE INTESTINE
LUNGS
MAMMALS
MICE
NEUTRONS
NUCLEI
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ODD-EVEN NUCLEI
ORGANS
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
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REPAIR
RESPIRATORY SYSTEM
RODENTS
VERTEBRATES
X RADIATION
YEARS LIVING RADIOISOTOPES