Influence of random daughter exposure rate, unattachment fraction, and disequilibrium on occurrence of lung tumors
Technical Report
·
OSTI ID:5391248
Groups of male, specific-pathogen-free (SPF), Wistar rats were exposed to several concentrations of radon daughters and uranium ore dust to clarify the roles of exposure rate, unattached RaA daughters, and the degree of radon daughter disequilibrium, in the development of respiratory system disease. Modeled, human-dosimetric data indicate that the dose to sensitive tissues of the respiratory tract increases with increasing radon-daughter unattachment fraction and degree of disequilibrium. Experimental verification of these dose-effect relationships is needed to protect the health of workers and of the public exposed to radon-daughter environments. Data bearing on these relationships as well as updated results of experiments designed to test the role of radon-daughter exposure rate on lung-tumor incidence are reported. 13 references, 3 tables.
- Research Organization:
- Pacific Northwest Lab., Richland, WA (USA)
- DOE Contract Number:
- AC06-76RL01830
- OSTI ID:
- 5391248
- Report Number(s):
- PNL-SA-11571; CONF-831049-2; ON: DE84003957
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560162* -- Radionuclide Effects
Kinetics
& Toxicology-- Animals
Plants
Microorganisms
& Cells
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
DATA
DAUGHTER PRODUCTS
DISEASES
DOSE RATES
DOSE-RESPONSE RELATIONSHIPS
DUSTS
ELEMENTS
EQUILIBRIUM
EXPERIMENTAL DATA
FLUIDS
GASES
INFORMATION
INHALATION
INTAKE
ISOTOPES
MAMMALS
NEOPLASMS
NONMETALS
NUMERICAL DATA
ORES
RADIATION EFFECTS
RADIOINDUCTION
RADON
RARE GASES
RATS
RESPIRATORY SYSTEM DISEASES
RODENTS
URANIUM ORES
VERTEBRATES
Kinetics
& Toxicology-- Animals
Plants
Microorganisms
& Cells
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
DATA
DAUGHTER PRODUCTS
DISEASES
DOSE RATES
DOSE-RESPONSE RELATIONSHIPS
DUSTS
ELEMENTS
EQUILIBRIUM
EXPERIMENTAL DATA
FLUIDS
GASES
INFORMATION
INHALATION
INTAKE
ISOTOPES
MAMMALS
NEOPLASMS
NONMETALS
NUMERICAL DATA
ORES
RADIATION EFFECTS
RADIOINDUCTION
RADON
RARE GASES
RATS
RESPIRATORY SYSTEM DISEASES
RODENTS
URANIUM ORES
VERTEBRATES