Damaging effects of visible light. Progress report

Technical Report · Mon Feb 01 04:00:00 EST 1982

OSTI ID:5386509

Williams, T P; Baker, B N

The right eyes of anesthetized, ten week old albino rats are exposed to constant photon fluxes at 6 wavelengths for 6 hours. The left eye of each animal is patched during the exposure and is used as control. Histologic examination of retinal sections disclosed a region in the superior retina which is more damaged than are other areas. Attempting to ascertain an action spectrum by measuring ONL lost in this sensative region fails. However, it is shown that, when ONL thickness is integrated over the entire retinal sections, a rhodopsin action-spectrum emerges. It is concluded that (i) retinal light damage in the albino rat under these conditions is rhodopsin mediated; and (ii) assessment of the extent of damage is best made by some method which integrates over the entire retinal section. The latter methodology is not routinely incorporated into studies of retinal light-damage but probably should be.

• Research Organization: Florida State Univ., Tallahassee (USA)
• DOE Contract Number: AS05-78OR06021
• OSTI ID: 5386509
• Report Number(s): DOE/OR/06021-4; ON: DE82011597
• Country of Publication: United States
• Language: English

Related Subjects

551000 -- Physiological Systems
560400* -- Other Environmental Pollutant Effects
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BODY
BODY AREAS
ELECTROMAGNETIC RADIATION
EYES
FACE
HEAD
HISTOLOGICAL TECHNIQUES
MAMMALS
ORGANS
PATHOLOGICAL CHANGES
PIGMENTS
RADIATIONS
RATS
RETINA
RODENTS
SENSE ORGANS
VERTEBRATES
VISIBLE RADIATION