Intestinal absorption of dietary fat from a liquid diet perfused in rats at a submaximum level
Journal Article
·
· Am. J. Clin. Nutr.; (United States)
OSTI ID:5381227
The small intestine of rats was perfused in vivo for 2 h with a nutritionally complete liquid diet (68% calories from fat as corn oil). As the perfusion increased from 106 mg/2 h, the intestinal disappearance of the /sup 14/C-triolein marker remained proportional to the load up to 2359 mg fat/2 h. Despite a decrease in absorption from 70 to 17%, this represents a very large fat intake. Fat absorption improved when medium-chain triglycerides or octanoic acid replaced corn oil (both p less than 0.01). Linoleic acid was absorbed from the diet less than corn oil (p less than 0.01). Dry ox bile reduced fat absorption (p less than 0.05); lipase and an antacid had no effect. Corn oil perfused alone was absorbed better than from the diet (p less than 0.01). Data with /sup 14/C-triolein was confirmed by dry-weight disappearance of the diet and by net intestinal water balance. Usual feeding underutilizes a large reserve for fat absorption. This reserve should be considered in therapeutic nutrition.
- Research Organization:
- Univ. of Cincinnati, OH (USA)
- OSTI ID:
- 5381227
- Journal Information:
- Am. J. Clin. Nutr.; (United States), Journal Name: Am. J. Clin. Nutr.; (United States) Vol. 47:2; ISSN AJCNA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Effect of diet on triolein absorption in weanling rats
Effect of dietary fat on plasma glutathione peroxidase levels and intestinal absorption of /sup 75/Se-labeled sodium selenite in chicks
Effect of bile diversion on satiety and fat absorption from liquid and solid dietary sources
Journal Article
·
Sun Dec 31 23:00:00 EST 1989
· American Journal of Physiology; (USA)
·
OSTI ID:6994470
Effect of dietary fat on plasma glutathione peroxidase levels and intestinal absorption of /sup 75/Se-labeled sodium selenite in chicks
Journal Article
·
Tue May 01 00:00:00 EDT 1984
· J. Nutr.; (United States)
·
OSTI ID:6307534
Effect of bile diversion on satiety and fat absorption from liquid and solid dietary sources
Journal Article
·
Wed Nov 30 23:00:00 EST 1988
· J. Surg. Res.; (United States)
·
OSTI ID:6605150
Related Subjects
550501* -- Metabolism-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ABSORPTION
ANIMALS
BILE
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CARBON 14 COMPOUNDS
CARBOXYLESTERASES
DIET
DIGESTIVE SYSTEM
DISPERSIONS
ENZYMES
ESTERASES
ESTERS
FATS
GASTROINTESTINAL TRACT
HYDROLASES
INTESTINAL ABSORPTION
INTESTINES
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
LIPASE
LIPIDS
MAMMALS
MATERIALS
MIXTURES
OILS
ORGANIC COMPOUNDS
ORGANS
OTHER ORGANIC COMPOUNDS
PERFUSED ORGANS
RATS
RODENTS
SMALL INTESTINE
SOLUTIONS
TRACER TECHNIQUES
TRIGLYCERIDES
TRIOLEIN
UPTAKE
VERTEBRATES
59 BASIC BIOLOGICAL SCIENCES
ABSORPTION
ANIMALS
BILE
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CARBON 14 COMPOUNDS
CARBOXYLESTERASES
DIET
DIGESTIVE SYSTEM
DISPERSIONS
ENZYMES
ESTERASES
ESTERS
FATS
GASTROINTESTINAL TRACT
HYDROLASES
INTESTINAL ABSORPTION
INTESTINES
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
LIPASE
LIPIDS
MAMMALS
MATERIALS
MIXTURES
OILS
ORGANIC COMPOUNDS
ORGANS
OTHER ORGANIC COMPOUNDS
PERFUSED ORGANS
RATS
RODENTS
SMALL INTESTINE
SOLUTIONS
TRACER TECHNIQUES
TRIGLYCERIDES
TRIOLEIN
UPTAKE
VERTEBRATES