Effect of dietary copper and sucrose on catecholamine concentrations in the adrenal medulla
Conference
·
· FASEB Journal (Federation of American Societies for Experimental Biology); (United States)
OSTI ID:5371818
- Kansas State Univ., Manhattan (United States) KCOM, Kirksville, MO (United States) Air Force/SAM/RZP, Brooks AFB, TX (United States)
The severity of copper (Cu) deficiency in the rat is enhanced by dietary sucrose. Possible interactive effects of Cu status and sucrose on catecholamine concentrations in the adrenal medulla were investigated in Cu deficient rats fed a diet were investigated in Cu deficient rats fed a diet containing either glucose or sucrose, as compared with respective Cu-adequate controls. Catecholamines were analyzed by an HPLC method using 3,4-dihydroxybenxylamine as the internal standard. Cu deficiency caused pronounced decreases in norepinephrine and epinephrine, with no significant effect on dopamine, as expressed in nmoles/mg tissue. Dietary sucrose showed no appreciable effect on catecholamines in the adrenal medulla. The adrenal glands were markedly enlarged in Cu-deficient rats, whether fed glucose or sucrose. Adrenal weights were not affected by dietary sucrose. Data indicate that the increased severity of copper deficiency due to sucrose feeding is not associated with changes in adrenal catecholamine output.
- OSTI ID:
- 5371818
- Report Number(s):
- CONF-9104107--
- Conference Information:
- Journal Name: FASEB Journal (Federation of American Societies for Experimental Biology); (United States) Journal Volume: 5:4
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADRENAL GLANDS
AMINES
ANIMALS
AROMATICS
BIOLOGICAL EFFECTS
BIOSYNTHESIS
BODY
CARBOHYDRATES
CATECHOLAMINES
CHROMATOGRAPHY
COPPER
DISACCHARIDES
ELEMENTS
ENDOCRINE GLANDS
GLANDS
HYDROXY COMPOUNDS
LIQUID COLUMN CHROMATOGRAPHY
MAMMALS
METABOLISM
METALS
NUTRITIONAL DEFICIENCY
OLIGOSACCHARIDES
ORGANIC COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
PHENOLS
POLYPHENOLS
RATS
RODENTS
SACCHARIDES
SACCHAROSE
SEPARATION PROCESSES
SYNTHESIS
TRANSITION ELEMENTS
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADRENAL GLANDS
AMINES
ANIMALS
AROMATICS
BIOLOGICAL EFFECTS
BIOSYNTHESIS
BODY
CARBOHYDRATES
CATECHOLAMINES
CHROMATOGRAPHY
COPPER
DISACCHARIDES
ELEMENTS
ENDOCRINE GLANDS
GLANDS
HYDROXY COMPOUNDS
LIQUID COLUMN CHROMATOGRAPHY
MAMMALS
METABOLISM
METALS
NUTRITIONAL DEFICIENCY
OLIGOSACCHARIDES
ORGANIC COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
PHENOLS
POLYPHENOLS
RATS
RODENTS
SACCHARIDES
SACCHAROSE
SEPARATION PROCESSES
SYNTHESIS
TRANSITION ELEMENTS
VERTEBRATES