Stability of Bacillus pumilus spore strips used for monitoring radiation sterilization

Journal Article · Tue Jun 01 00:00:00 EDT 1976 · Appl. Environ. Microbiol.; (United States)

OSTI ID:5370775

Prince, H N

Dried Bacillus pumilus spore strips had a stable D-value of 0.17 to 0.18 Mrad after 1 year at 5 or 25 C, but resistance was lost at 35 C. Refrigeration did not have an adverse effect on resistance to irradiation. The presence of water at the time of initial preparation increased this resistance to 0.23 to 0.25 Mrad. Proper drying is essential to achieve reproducible results in sterility tests using USP-type biological indicators.

• Research Organization: Gibraltar Biological Labs., Inc., Fairfield, NJ
• OSTI ID: 5370775
• Journal Information: Appl. Environ. Microbiol.; (United States), Journal Name: Appl. Environ. Microbiol.; (United States) Vol. 31:6; ISSN AEMID
• Country of Publication: United States
• Language: English

Related Subjects

560131* -- Radiation Effects on Microorganisms-- Basic Studies-- (-1987)
560133 -- Radiation Effects on Microorganisms-- Radiosterilization of Medical Supplies-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BACILLUS
BACTERIA
BACTERIAL SPORES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL INDICATORS
COBALT 60
COBALT ISOTOPES
ELECTROMAGNETIC RADIATION
GAMMA RADIATION
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MICROORGANISMS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-ODD NUCLEI
RADIATIONS
RADIOISOTOPES
RADIOSENSITIVITY
RADIOSENSITIVITY EFFECTS
RADIOSTERILIZATION
SPORES
STERILIZATION
STORAGE
TEMPERATURE DEPENDENCE
TIME DEPENDENCE
YEARS LIVING RADIOISOTOPES