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Intracranial metastases: behavioral patterns related to primary site and results of treatment by whole brain irradiation

Journal Article · · Int. J. Radiat. Oncol., Biol. Phys.; (United States)
;
Three hundred and fifty cases of tumors that metastasized to the brain and treated by radiotherapy were reviewed. The majority of patients had either lung (46%) or breast (42%) primaries. Eighty percent of the patients had other sites of metastatic involvement. Seventy-five percent of the patients improved after cranial irradiation. The median survival was less than 6 months, regardless of the primary disease or the dose employed. No subgroup could be identified that might benefit from a more aggressive treatment regimen. Radiation treatment in the range of 2000 rad in one week or 3000 rad in two weeks is recommended for palliation of metastatic cancer to the brain.
Research Organization:
Univ. of Texas System Cancer Center, Houston
OSTI ID:
5370573
Journal Information:
Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 6:1; ISSN IOBPD
Country of Publication:
United States
Language:
English

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Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BONE MARROW
BRAIN
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
COBALT 60
COBALT ISOTOPES
DATA
DATA COMPILATION
DATA FORMS
DISEASES
DOSE RATES
ELECTROMAGNETIC RADIATION
GAMMA RADIATION
GLANDS
GRAPHS
HEART
HEMATOPOIETIC SYSTEM
INFORMATION
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LUNGS
MAMMARY GLANDS
MEDICINE
METASTASES
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NERVOUS SYSTEM
NUCLEAR MEDICINE
NUCLEI
NUMERICAL DATA
ODD-ODD NUCLEI
ORGANS
PATIENTS
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
RESPIRATORY SYSTEM
SIDE EFFECTS
SURVIVAL CURVES
SURVIVAL TIME
SYMPTOMS
TABLES
THERAPY
TISSUES
X RADIATION
YEARS LIVING RADIOISOTOPES