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1949 outbreak of Pontiac fever-like illness in steam condenser cleaners. [Legionella pneumophila]

Journal Article · · Arch. Environ. Health; (United States)
OSTI ID:5352764
A 1949 outbreak of flu-like illness in steam-turbine condenser cleaners was investigated in 1979. Clinical and epidemiologic features matched those in previously described outbreaks of nonpneumonic legionellosis (Pontiac fever). Titers by indirect immunofluorescence using polyvalent Legionella pneumophila antigen were significantly higher for late convalescent-phase serum samples from condenser workers than for control serum samples submitted to the Centers for Disease Control. The workers who had cleaned the condensers on several occasions had experienced recurrent illness associated with these operations, which might support the theory that nonpneumonic legionellosis is caused by an immune reaction to an inhaled antigen or bacterial toxin of L. pneumophila, rather than a true infection.
Research Organization:
Centers for Disease Control, Atlanta, GA
OSTI ID:
5352764
Journal Information:
Arch. Environ. Health; (United States), Journal Name: Arch. Environ. Health; (United States) Vol. 40:1; ISSN AEHLA
Country of Publication:
United States
Language:
English