Electrospray ionization combined with ion trap mass spectrometry

Journal Article · Sun Jul 01 04:00:00 EDT 1990 · Analytical Chemistry (Washington); (United States)

DOI:https://doi.org/10.1021/ac00212a016· OSTI ID:5349084

Van Berkel, G J; Glish, G L; McLuckey, S A ^[1]

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1. Oak Ridge National Laboratory, TN (USA)

Ions from a variety of molecules, formed via electrospray, have been injected into and analyzed with a quadrupole ion trap mass spectrometer. Examples are shown in which one or more stages of mass spectrometry (e.g., mass spectrometry/mass spectrometry) have been performed on both multiply charged anions and cations. Compounds for which data are described include the disodium salt of 2-hydroxynapthalene-3,6-disulfonic acid, Direct Red 81, bradykinin, melittin, cytochrome c, myoglobin, and bovine albumin. For some compounds, notable the sulfonates, evidence is presented for the injection of highly solvated ions that desolvate within the ion trap. The cations derived from the peptides, on the other hand, appear to be essentially desolvated prior to injection into the ion trap.

• DOE Contract Number: AC05-84OR21400
• OSTI ID: 5349084
• Journal Information: Analytical Chemistry (Washington); (United States), Journal Name: Analytical Chemistry (Washington); (United States) Vol. 62:13; ISSN 0003-2700; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
550200 -- Biochemistry
59 BASIC BIOLOGICAL SCIENCES
AROMATICS
BRADYKININ
CARBOXYLIC ACIDS
CONDENSED AROMATICS
CYTOCHROMES
GLOBINS
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
HYDROCARBONS
KININS
MASS SPECTROSCOPY
MEASURING METHODS
MYOGLOBIN
NAPHTHALENE
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PEPTIDES
PIGMENTS
POLYPEPTIDES
PORPHYRINS
PROTEINS
SPECTROSCOPY
SULFONIC ACIDS