Head and neck neoplasia following irradiation for benign conditions
Journal Article
·
· Head Neck Surg.; (United States)
A retrospective review of 143 patients with head or neck tumors who had received radiation therapy in the head and neck area for benign conditions during childhood or adolescence was conducted. This included an analysis of 1,080 patients from the Evanston Hospital Irradiated Thyroid Evaluation Clinic, which was established to define the relationship between irradiation and the subsequent development of thyroid neoplasia. The data support the following concepts of irradiation-induced neoplasia: (1) The thyroid, parathyroid, and salivary glands can develop benign and malignant changes after irradiation for benign conditions, with latent periods averaging about 30 years; (2) Once a glandular abnormality within the irradiated field appears, the risk of other glands in the field developing neoplastic changes is significantly increased.
- Research Organization:
- Department of Surgery, Evanston Hospital, IL
- OSTI ID:
- 5337391
- Journal Information:
- Head Neck Surg.; (United States), Journal Name: Head Neck Surg.; (United States) Vol. 4:2; ISSN HNSUD
- Country of Publication:
- United States
- Language:
- English
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· Head Neck Surg.; (United States)
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550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
560161* -- Radionuclide Effects
Kinetics
& Toxicology-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
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AGE GROUPS
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ENDOCRINE GLANDS
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NEOPLASMS
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ORGANS
PARATHYROID GLANDS
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RADIOTHERAPY
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SIDE EFFECTS
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62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
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BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
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BODY AREAS
CHILDREN
DELAYED RADIATION EFFECTS
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ENDOCRINE GLANDS
GLANDS
HEAD
LATENCY PERIOD
MEDICINE
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NUCLEAR MEDICINE
ORGANS
PARATHYROID GLANDS
RADIATION EFFECTS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SALIVARY GLANDS
SIDE EFFECTS
THERAPY
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