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Gated right ventricular studies using krypton-81m: comparison with first-pass studies using gold-195m

Journal Article · · J. Nucl. Med.; (United States)
OSTI ID:5330419
; ;
Krypton-81m, given by continuous i.v. infusion, has been successfully used for the equilibrium ECG-gated assessment of right ventricular function. We compared gated studies with 81mKr (half-life 13 sec) with first-pass studies using 195mAu (half-life 30.5 sec). Krypton studies analyzed using variable regions of interest (ROIs) led to a significantly higher calculated right ventricular ejection fraction (RVEF) than with a fixed ROI, both with and without background correction. The differences between first-pass studies and gated studies without background correction were significant (p less than 0.01), whereas they were not with background correction. These data suggest that large systematic errors exist in the calculation of RVEF depending on the analysis method and that background correction is important when different techniques are compared.
Research Organization:
St. Bartholomew's Hospital, London, England
OSTI ID:
5330419
Journal Information:
J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 5; ISSN JNMEA
Country of Publication:
United States
Language:
English

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Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC USES
ELECTRON CAPTURE RADIOISOTOPES
ERRORS
EVEN-ODD NUCLEI
GOLD 195
GOLD ISOTOPES
HEART
HEAVY NUCLEI
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KRYPTON 81
KRYPTON ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SECONDS LIVING RADIOISOTOPES
USES
YEARS LIVING RADIOISOTOPES