Biological markers in chromium exposure assessment: Confounding variables

Journal Article · Mon Jul 01 04:00:00 EDT 1991 · Archives of Environmental Health; (United States)

DOI:https://doi.org/10.1080/00039896.1991.9937454· OSTI ID:5317744

Bukowski, J A; Goldstein, M D; Johnson, B B ^[1]

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1. Division of Science and Research, New Jersey Department of Environmental Protection, Trenton (USA)

An estimated two million tons of chromate production waste pollution has caused a major environmental and public health concern in Hudson County, New Jersey. As part of an occupational exposure assessment, urinary and red blood cell (RBC) chromium measurements were performed on 52 state employees who worked either near a contaminated site or elsewhere. Samples were collected so as to minimize contamination, and they were analyzed using sensitive techniques. These workers also completed a questionnaire that addressed potentially important third variables. Individual analyses suggested that exercise, drinking beer, past employment in chromium-related occupations, and diabetic status had an important effect on urinary chromium levels. These variables were entered into a regression model and were all found to be significant predictors of urinary chromium level (p less than .10). Some variables were also examined for their influence on RBC chromium level, but none had a measurable effect.

• OSTI ID: 5317744
• Journal Information: Archives of Environmental Health; (United States), Journal Name: Archives of Environmental Health; (United States) Vol. 46:4; ISSN AEHLA; ISSN 0003-9896
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL MARKERS
CHROMIUM
DEVELOPED COUNTRIES
DIABETES MELLITUS
DIET
DISEASES
ELEMENTS
ENDOCRINE DISEASES
FEDERAL REGION II
HAZARDS
HEALTH HAZARDS
METABOLIC DISEASES
METABOLISM
METALS
NEW JERSEY
NORTH AMERICA
OCCUPATIONAL EXPOSURE
RISK ASSESSMENT
TRANSITION ELEMENTS
USA