Critical review of epidemiologic studies related to ingested asbestos

Journal Article · Tue Nov 01 04:00:00 EST 1983 · Environ. Health Perspect.; (United States)

DOI:https://doi.org/10.1289/ehp.835349· OSTI ID:5317276

Marsh, G M

Thirteen epidemiologic studies of ingested asbestos conducted in five areas of the US and Canada were evaluated for the definitiveness and applicability regarding the development of ambient water quality standards. Associations between asbestos in water supplies and cancer mortality or incidence in humans were found in one or more studies dealing with neoplasms in the esophagus, stomach, small intestine, colon, rectum, gallbaldder, pancreas, peritoneum, lungs, pleura, prostate, kidneys, brain and thyroid as well as leukemia. However, no single study nor aggregate of studies existed that would establish risk levels from ingested asbestos. It is recommended that the integrated ecologic data to date be used to generate a rough priority of specific etiologic hypotheses that should be tested in the original settings or in independent study populations using studies designed at the more definitive individual level, such as case-control studies. 25 references, 7 tables.

• Research Organization: Pittsburgh Univ., PA
• OSTI ID: 5317276
• Journal Information: Environ. Health Perspect.; (United States), Journal Name: Environ. Health Perspect.; (United States) Vol. 53; ISSN EVHPA
• Country of Publication: United States
• Language: English

Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ASBESTOS
BILIARY TRACT
BODY
BRAIN
CANADA
CENTRAL NERVOUS SYSTEM
COMPARATIVE EVALUATIONS
CORRELATIONS
DIGESTIVE SYSTEM
DISEASES
DOCUMENT TYPES
ENDOCRINE GLANDS
ENVIRONMENTAL QUALITY
EPIDEMIOLOGY
ESOPHAGUS
GASTROINTESTINAL TRACT
GLANDS
HAZARDS
HEALTH HAZARDS
HEMIC DISEASES
INGESTION
INTAKE
INTESTINES
KIDNEYS
LARGE INTESTINE
LEUKEMIA
LUNGS
MALE GENITALS
MEMBRANES
NEOPLASMS
NERVOUS SYSTEM
NORTH AMERICA
ORGANS
PANCREAS
PERITONEUM
PLEURA
PROSTATE
RECTUM
RESPIRATORY SYSTEM
REVIEWS
RISK ASSESSMENT
SEROUS MEMBRANES
SMALL INTESTINE
STANDARDS
STOMACH
THYROID
USA
WATER QUALITY