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Comparing epidemiologic studies of ingested asbestos for use in risk assessment

Journal Article · · Environ. Health Perspect.; (United States)
DOI:https://doi.org/10.1289/ehp.835399· OSTI ID:5434312
Risk assessment studies make use of epidemiologic data in various ways to calculate the dose-response relationship between exposure levels and adverse effects; to establish ranges of exposure known to be safe or unsafe; to verify an endpoint in humans derived from a route or species extrapolation; to support assumptions necessary for performing extrapolation procedures. Cohort studies of inhalation exposure were used to devise the EPA's Ambient Water Quality Criteria (AWQC) for Asbestos. Epidemiological studies of ingested asbestos, all of geographical correlation design, were compared on the basis of their ability to add information in support of both the route extrapolation and low-dose extrapolation used in this risk assessment. 16 references, 4 tables.
Research Organization:
Environmental Protection Agency, Cincinnati, OH
OSTI ID:
5434312
Journal Information:
Environ. Health Perspect.; (United States), Journal Name: Environ. Health Perspect.; (United States) Vol. 53; ISSN EVHPA
Country of Publication:
United States
Language:
English